Memphis Depay was not actually fit enough to start for the Netherlands against Senegal due to his injury issue for Barcelona this season, but he partakes in the final 30 minutes of the game contest.
The attacker player, who conceived 42 goals at international level, could now come in for a start here to replace Vincent Janssen, with Gakpo and Steven Bergwijn also set to feature in the final third of the field.
There are not likely to be any changes elsewhere, with a 3-5-2 formation set to include Frenkie de Jong and Steven Berghuis in midfield, and Denzel Dumfries and Daley Blind in the full-back areas.
Marten de Roon was an injury doubt ahead of the contest with Senegal, but the midfielder also featured off the bench last time out, and he is again expected to receive minutes at some stage of the contest.
As for Ecuador, Valencia suffered an injury to his knee during the clash with Qatar, but the 33-year-old is expected to be available to start this match.
Valencia is the national team’s all-time leading goalscorer with 37, while he now has five strikes at World Cups, so the medical team will be working to ensure that he is able to feature here.
Head coach Alfaro could make just the one change from the side that started against Qatar, with Jeremy Sarmiento potentially being introduced for Michael Estrada in what would be a change of shape.
Robert Arboleda is pushing for a spot at the back, though, and the 31-year-old will come into the manager’s thinking ahead of kickoff on Friday.
Possible starting lineup for Netherlands:
Noppert; De Ligt, Van Dijk, Ake; Dumfries, F de Jong, Berghuis, Blind; Gakpo; Memphis, Bergwijn
Possible starting lineup for Ecuador:
Galindez; Preciado, Torres, Hincapie, Estupinan; Plata, Caicedo, Mendez, Ibarra; Sarmiento; Valencia